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AstraZeneca announced high-status unusual background presented today at the 24th Collegium Internationale Neuro-Psychopharmacologicum (CINP) prior arrangement contained by Paris, which back wakeful that patients beside bipolar depreciation who be treat with SEROQUEL (quetiapine) quality chief loose change in symptom of anxiety associated enclosed knees of the anarchy, from in place of over-hasty as the most jagged week of stimulating.1 The data from the exploration show SEROQUEL to be to a large extent more forceful than placebo and ably tolerate in favour of the treatment of anxiety symptoms in bipolar depression. Furthermore, the data show that SEROQUEL works at a fast pace to dampen the symptoms of anxiety, own a significant effect by the side of symptoms in the first week of treatment and continuing to advance symptoms through the 8 weeks of treatment.1 These new data presented today are from the large-scale, multi-centred, BOLDER hearing presented final month at the157th American Psychiatric Association (APA) meeting, which found SEROQUEL to be an effective and well-tolerated agent for the treatment of depressive symptoms associated with bipolar disorder.2 “Many patients with bipolar depression experience tenacious anxiety, and sometimes this be more disquieting than the depressive symptoms. Symptoms of anxiety are agreed to be associated with suicide attempt in bipolar disorder. Indeed, anxiety symptoms are again and again the starting point why patients aim treatment in the first vertebrae.

Therefore, it is important for medication that occupation in bipolar depression to be effective treatment for anxiety, and that they work quickly and effectively,” comment Dr Joseph Calabrese, Co-Director of the National Institute of Mental levitra professional Bipolar Research Center at University Hospitals of Cleveland and Case Western Reserve University School of Medicine, and head trial investigator. “These data show that with SEROQUEL, psychiatrist have a future new treatment for bipolar depression, that is to read out effective and works quickly for both depression and anxiety symptoms.” The BOLDER trial be an 8 week, multi-centred, randomised, double-blind, placebo-controlled study involving 542 patients with a diagnosis of bipolar I or II disorder. Patients received 300mg/day SEROQUEL or 600mg/day SEROQUEL, or placebo. The grades of this trial show: — Patients taking SEROQUEL 600 mg/day and 300mg/day have a significantly greater improvement (p<0.05) in connote Hamilton Rating Scale for Anxiety (HAM-A) ranking versus placebo in any way sentence point from week one through to week 8 (-8.75, -8.64 vs -5.5).

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